66 million Americans live in rural counties where stroke incidence runs 23–30% higher than in urban areas. Of GWTG-Stroke patients (2017–2019), only 4.5% are treated at rural hospitals. Thrombolysis utilization: 31.7% rural vs. 43.5% urban. Door-to-needle within 45 minutes: 33.0% rural vs. 44.7% urban. Of roughly 1,383 Critical Access Hospitals, about 5.6% are ASRH-certified.
Where the time goes:
Most CAHs have no on-site neuroradiology. Legacy teleradiology turnaround runs in hours.
ED coverage often falls to family practitioners without specialist backup.
Alteplase’s 60-minute infusion forces the spoke hospital to hold the patient rather than transfer.
Up to 81% of rural patients arrive past the 4.5-hour treatment window.
What changes the timeline:
AI triage on non-contrast CT flags intracranial hemorrhage in seconds at the scanner. The broadband and teleradiology bottleneck stops mattering.
Mobile DICOM lets a remote stroke specialist scroll the same CT on a phone and authorize treatment in real time.
Tenecteplase, now Class 1 in the 2026 AHA/ASA Guideline, replaces a 60-minute infusion with a 5-second bolus. The spoke can bolus and ship.
PurpleAI is building this stack for the rural ED. Hyper Insight-ICH (FDA 510(k)-cleared) for hemorrhage triage. Mobile DICOM built for the family practitioner reading a CT at 2 a.m. without a neurologist on call.

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