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New benchmark for post-stroke outcome prediction

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🧠 A new benchmark for post-stroke outcome prediction is here.

Olsson et al. (2026, Scientific Reports) trained explainable ML models on 506 acute ischemic stroke patients across four stroke units in Sweden, predicting 3-month functional outcome (mRS > 2):

📊 AUROC 0.900–0.906

📈 AUPRC 0.773 ± 0.080 (MLP, best model)

🎯 Sensitivity 0.655 | Specificity 0.920

Top signals 👇

⚡ NIHSS dominated clinical features

🧬 Brain-derived tau (BD-tau) led blood biomarkers

🔍 SHAP interpretability across XGBoost + MLP + regularized logistic regression

🔗 Full paper: https://lnkd.in/gCxQsddg

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